Intermittent Fasting has many health benefits

Why has intermittent fasting (IF) become so popular in the past few years?

One of the main reasons is simplicity. There are a million and one diets that involve specific foods or nutrients, but IF skirts all those details. Let’s see what the main types of IF are, and what the evidence shows about weight loss and other health effects.

IF variants

Also known as time-restricted feeding,[1] IF alternates periods of normal food intake with extended periods (usually 16–48 h) of low-to-no food intake. This approach lends itself to different variants, including those:

  • Alternate-Day Fasting (also known as Alternate-Day Modified Fasting). This diet can take different forms: you can eat over 12 hours then fast for 36 hours; you can eat over 24 hours then fast for 24 hours; or you can eat normally over 24 hours then eat very little (about 500 kcal) over the next 24 hours.
  • Eat-Stop-Eat. You fast or severely restrict calories for 24 hours, either at regular intervals (two days per week in the 5:2 Diet) or just from time to time.
  • Random Meal Skipping. You skip meals at random throughout the week.
  • Feeding Window. You can only eat during a set period of time every day (from 10 a.m. to 6 p.m, for instance).

Should you decide to try intermittent fasting, pick a variant you think you can stick with for at least a few weeks.

Effects on Weight

Yes, IF can lead to weight loss,[2] but all variants may not be equally efficacious. For instance, simply skipping breakfast led to weight loss in one study[3] but not in another.[4] In both studies, the control groups were provided with a standard breakfast, such as oatmeal, but neither group was restricted in what they could eat the rest of the day.

It’s also possible that people with more weight to lose may benefit more from an IF approach, but one thing is sure: if you compensate for the meals you skipped by eating more later in the day, or the next day, or the next, you won’t lose weight. The weight-loss equation is simple: you need to ingest less calories than you burn. IF is just one way to make this happen, but it is a way that some people find easier than the more common “eat smaller meals” approach.

To lose weight, you need to burn more than you eat — or, conversely, to eat less than you burn. Some people find this goal easier to reach through intermittent fasting than through the traditional “smaller meals” approach.

Effects on Health

The body of evidence on IF is still relatively small, but a growing number of studies have reported improvements in various health markers aside from weight, notably lipids.[1] Further, those studies suggest that IF may provide unique metabolic benefits over the “eat smaller meals” approach.

The most intriguing of those benefits, but also the most debated, is a longer life. Fasting can kick-start some regenerative processes in the body,[5] and extended lifespans from caloric restriction have been reported in many animal models[6] (but not all[7]). Keep in mind, however, that those animals were either fed low-calorie diets or rotated through periods of fasting for most of their lives. It is unknown if IF can extend the lifespan of human beings, and if it can, which variant is best and how many weeks, months, or years are required to make a difference.

Assessing the potential metabolic benefits of IF is a long-term endeavor. As a systematic review of the literature noted in 2015,[8] preliminary evidence looks promising, but solid research is still sparse, so that “further research in humans is needed before the use of fasting as a health intervention can be recommended”.