Nicotinamide Riboside is said to repair functioning of the mitochondria which power energy generation in every cell in our bodies.
This is supposed to “turn back the clock” and make us younger, and repair many (not all) of the ravages of aging.
There have been several research studies with NR and NMN that do show great promise, but also leave some questions to be answered by other studies that are currently underway
In this article we examine the research to date on Nicotinamide Riboside.
TREATMENT OF SPECIFIC CONDITIONS WITH NICOTINAMIDE RIBOSIDE
NR has been shown to increase NAD+ levels in humans.
This results in speculation that NR might be useful in treating many age related health conditions such as:
- metabolic syndrome
- erectile dysfunction
- rheumatoid arthritis
- prostate cancer
- hearing loss
- appetite suppression
Testing is currently underway to evaluate Nicotinamide Riboside for treating many of these symptoms.
Research studies with mice have demonstrated that supplementation with NR:
- Improves cognition in mice with Alzheimers (32) 2013
- Lowered cholesterol, improved hepatic inflammation in tumors (33) 2015
To date the only completed testing with human subjects for treatment of specific conditions is:
- Protects against hearing loss caused by noise exposure (34) 2014
Many studies are currently ongoing such as an obesity study underway by the Novo Nordisk Foundation Center for Basic Metabolic Research.
Decreased NAD+ levels are implicated in many age related disease and disabilities.
NR does raise NAD+ levels in human tests lasting 1 week. Long term testing is not yet complete.
NR has been shown to improve or protect against some age related problems, and shows potential for much more.
In addition to protecting various organs such as liver and kidney, heart, lungs, and neuro-protection, NR is marketed as a potential anti-aging therapy. It may yet prove to be of some benefit in slowing some aspects of the aging process, but as yet there is no definitive proof.