Digestive Health

Aug, 2016

Fruit and vegetable consumption and risk of cholecystectomy: a prospective cohort study of women and men.

Cholecystectomy is the surgical removal of the gallbladder, a common treatment for gallstones or other complications.

This prospective observational study in adults suggests that eating a lot of fruits and vegetables may reduce the risk of needing a cholecystectomy in 48–60 year old women. No significant association was detected in men or younger women.

Zinc carnosine works with bovine colostrum in truncating heavy exercise-induced increase in gut permeability in healthy volunteers.

Intense exercise may cause gut symptoms. In some cases, it may also lead to a heat stroke believed to be caused by increased intestinal permeability to toxins.

This study showed that supplementing with zinc carnosine (ZC) — either alone or in combination with colostrum — strengthened the intestinal lining and reduced adverse effects. The benefits were greatest when both colostrum and ZC were taken together.

July, 2016

Dietary silver nanoparticles can disturb the gut microbiota in mice.

Silver nanoparticles (SNP) are increasingly being used by the food industry. SNPs have antibacterial activity and increase the shelf-life of processed food products.

This study in mice showed that SNPs didn’t cause any signs of toxicity. However, they disturbed the gut microbiota by reducing bacterial diversity. SNPs likely have similar effects in humans and potentially affect health.


Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.

This randomized controlled trial in patients with irritable bowel syndrome (IBS) showed that supplementing with 50,000 IU of vitamin D3 every two weeks for 6 months improved quality of life.

Specifically, it reduced several IBS symptoms, such as abdominal pain, flatulence, distention and rumbling.

Effectiveness of nutritional treatment and synbiotic use on gastrointestinal symptoms reduction in HIV-infected patients: randomized clinical trial.

Synbiotics are supplements containing both probiotics and prebiotics (beneficial bacteria and the fiber that nourishes them). This controlled trial examined the effects of supplementing with synbiotics on digestive problems in HIV patients.

Digestive problems are a common complaint among people with HIV and AIDS. The study showed that probiotics plus 6 grams of fructooligosaccharides had no significant effects on digestive symptoms, compared to a placebo (maltodextrin).


Gut Virome and Inflammatory Bowel Disease.

Not only is the human digestive system home to billions of bacteria, it also hosts a wide variety of viruses, which are collectively known as the gut virome.

Similarly to gut bacteria, gut viruses may be implicated in chronic diseases and immune disorders. This review discusses the potential role of the gut virome in chronic inflammation and inflammatory bowel disease.

The efficacy and safety of probiotics for prevention of chemoradiotherapy-induced diarrhea in people with abdominal and pelvic cancer: a systematic review and meta-analysis.

This review and meta-analysis evaluated the safety of probiotics for preventing diarrhea in people undergoing chemoradiotherapy for abdominal or pelvic cancer.

The reviewers concluded that probiotics may be useful for preventing or reducing chemoradiotherapy-induced diarrhea and adverse side effects are uncommon.

June, 2016

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