Frequently Asked Questions about Nicotinamide Adenine Dinucleotide (NAD⁺) and Nicotinamide Mononucleotide (NMN)
NAD⁺ is a coenzyme that is present in all living cells. Supplementing NAD⁺ levels leads to healthier cells. NAD⁺ levels decline naturally as we age. NAD⁺ works with the cell to bolster vital cellular processes leading to DNA optimization, sleep pattern regulation and energy formation.
NMN is a precursor molecule to NAD+. NMN works synergistically at the cellular level to increase sirtuin activity, optimize mitochondrial function, and restore levels of NAD+ as they were in youth.
NMN and NAD⁺ have no known side effects or contraindications when taken together or separately.
Humans only absorb 20% of nutrients we ingest through digestive system. Sublingual delivery is revolutionary – by avoiding first pass of the digestive system, NMN and NAD⁺ are absorbed directly into the bloodstream.
All of our raw ingredients are made and manufactured in the United States, and all of our products are manufactured in the United States under rigorous pharmaceutical and cGMP protocols.
All of our formulations are 100% natural and made by a patented, solvent-free based process.
To prevent contamination, we do not include the scoop in the jar itself.
It is best to keep the measuring scoop separate from the product.
We choose to follow pharmaceutical guidelines and offer scoops that are individually wrapped, which accompany the jar.
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport a small quantity of Nicotinamide Mononucleotide (NMN) directly into some cells.
However, this enzyme is only prevalent in the small intestine of older, sicker animals and humans.
The Slc12a8 enzyme was just discovered because it plays a very minor role, and does not transport a large enough quantity of NMN to have been noticed earlier.
NAD⁺ and NMN need to be slightly acidic, both to maintain stability, and improve sublingual absorption.
Our products vary between 4.0 and 4.5 pH, which is similar to the acidity of tomatoes on the pH scale.
Prolonged exposure could in theory contribute to loss of enamel, but less so than more acidic foods such as lemons or oranges.
The sublingual powder should be placed under the tongue to dissolve. It should not come in contact with the teeth.
Nicotinamide Adenine Dinucleotide (NAD⁺)
PURE NAD⁺ Sublingual Tablets
The only ingredients in NAD⁺ tablets are the NAD⁺ molecule itself and excipients essential to the formation of the tablet.
Recommended daily dosages of sublingual NAD⁺ are at least 400 mg, which equates to 3-4 tablets per day at minimum.
PURE NAD⁺ Powder
The only ingredient in PURE NAD⁺ Powder is the NAD⁺ molecule itself.
Recommended daily dosages of sublingual NAD⁺ are at least 400 mg, which equates to 3-4 scoops of PURE NAD⁺ Powder.
Liquid NAD⁺ Drops
Liquid NAD⁺ contains the molecule itself and organic non – GMO pharmaceutical gradeexcipients that are a natural way to ensure self-life and potency.
We chose to keep the glass pipette free of markings so the Liquid NAD⁺ does not come into contact with dye.
For the .5mL serving size, simply fill halfway and place under the tongue to dissolve.
Half full is .5mL, which delivers a 125 mg serving of NAD⁺.
We recommend 3-4 doses per day.
PURE NAD⁺ Nasal Spray
PURE NAD⁺ Nasal Spray contains the molecule itself and organic non – GMO pharmaceutical grade excipients that are a natural way to ensure self-life and potency. The Nasal Spray is safe and effecatious in the nasal cavity, subject to rigourous third party testing.
Two sprays of NAD⁺ Micromist deliver 12.5 mg each directly to the blood brain barrier, constituting a serving of 25 mg.
We recommend 3-4 servings per day.
Nicotinamide Mononucleotide (NMN)
PURE NMN Powder
The only ingredient in PURE NMN Powder is the NMN molecule itself.
Recommended daily dosages of sublingual NMN are at least 400 mg, which equates to 3-4 scoops of PURE NMN Powder.
PURE NMN Sublingual Tablets
The only ingredients in NMN tablets are the NMN molecule itself and an excipient essential to the formation of the tablet.
Recommended daily dosages of sublingual NMN are at least 400 mg, which equates to 3-4 tablets per day at minimum.
NAD⁺ Optimizer Series
MSM – Methylsulfonylmethane
Methylsulfonylmethane decreases inflammatory response to tumor necrosis factor-α in cardiac cells.
Curcumin aids in the management of oxidative and inflammatory conditions.
Boswellia Serratta contains acids responsible for inhibition of pro-inflammatory enzymes.
Berberine regulates glucose and lipid metabolism.
Silibinin (from Milk Thistle)
Silibinin Restores NAD+ levels and induces the
SIRT1/AMPK pathway in non-alcoholic fatty liver, while also increasing the bioavailability of Berberine.
Piperine is used to
increase bioavailability of Curcumin.
It is recommended to take 2-4 capsules per day at 650 mg each to suppress chronic inflammation which research shows is the leading consumer of NAD⁺ as we age.