Bryan Nettles, 58 – Faster, stronger, healthier

At 57 years old, I felt I was in pretty good shape from running, swimming or lifting weights 5-6 days a week. Yes, knee, hip, back and shoulder pains limited how much I could run or lift. I was slower and weaker than when I was young, but who isn’t?


December 2017
Not bad for 57 year old (I thought)

June 2 2018
after 3 months taking Sublingual NMN

July1 2018
Stronger than my 20’s

At 58 years old, I am back to running a 6 minute mile, lifting the heavier weights and carrying around MORE muscle than I had in my 20’s. Most amazing is, the improvements came from less than 3 months of taking frequent doses of sublingual NMN (under the tongue).

My personal experience has been that taking NMN sublingually (under the tongue) improves the effectiveness such that I achieved even better and faster results than the mice in Dr. Sinclairs’ experiments.

I am Bryan Nettles, owner of You can read more about NMN on our home page, and in our facebook users group.

Switch from NR to NMN mid 2017

I was taking Nicotinamide Riboside (NR) for a few years, but switched to Nicotinamide Mononucleotide (NMN) in 2017. I felt I was getting more benefit from the NMN, and was such a believer that we began producing our own NMN and selling it on in mid 2017.

There have been many studies with mice that demonstrate benefits for a wide range of health issues from supplementation with NMN. The most recent was published by Dr. Sinclair showing phenomenal muscle and vascular benefits.

Switch to sublingual delivery Feb 2018

I talk to customers a lot, and had been hearing from some who said they noticed much better results from taking NMN sublingual, so I started trying that in February 2018.

The nagging knee and hip pains that have bothered me the last few years  faded, so it wasn’t surprised that I was running much faster. But I was surprised to find I had more strength in the gym and I also started to notice some muscle growth returning that I had lost of the previous 10-15 years.

More frequent dosages April 2018

In early April I followed some other customers suggestions, and increased the frequency to 3-4 times a day, instead of 1-2. That resulted in even more improvement in strength and muscle building. Within a month, I was tossing around heavy dumbbells that I hadn’t touched in 10 years.

In late April, I thought, why not kick it up and see what happens. 6-8 doses a day quickly grew to 10-12 times a day.

The results have been truly spectacular. Most of the change between these 2 pictures were achieved over 6 weeks.

Why so frequent?

It was really by chance that I followed some customers recommendation to try more frequent dosages at first. Later, when it seemed to work, I decided to try taking some every hour when convenient.

I believe the increased effectiveness from sublingual delivery of NMN is because it reaches the bloodstream directly. However, NMN will be quickly filtered out by the liver where it is metabolized to NAD+. After that, it would be no more effective than NMN or NR capsules.

The chart at left shows NMN levels in the blood of mice are elevate for 15 minutes, after which it is converted to NAD+ in the liver. Human metabolism is slower, but it is likely NMN from sublingual delivery will also be present in the bloodstream for a less than an hour before it is filtered out by the liver. This was my reasoning for taking a dose of NMN sublingually every hour, when convenient.

Regaining ALL the muscle mass from my youth

I don’t quite push the same weights as I did in my 20’s (yet), but the muscle and vascularity are as good as ever, and in some places even better.

When I first started noticing the dramatic improvements I thought it was placebo effect. Then, when it continued I realized I was seeing some of the same benefits as Dr. Sinclair’s mice, with “younger” muscles. I thought I had “rolled back the clock” 10 years or so and was thrilled.

The progress continued and I began to feel I had the same strength and endurance from my 30’s, and was even more thrilled.

I was actually shocked that the progress accelerated and I regained ALL the muscle mass I had in my 20’s.


More muscle growth than when young – how is that possible?

Studies have demonstrated NO benefit from NMN in young mice. It doesn’t make them superstrong or improve the endurance of young mice.

Due to homeostasis,  NAD+ are not elevated in older mice or humans ABOVE what it was when young.

Yet I am now seeing muscle growth and vascularity that is better than what I had in my 20’s when I was lifting weights religiously. This extreme growth is of course entirely unexpected and didn’t make sense.

But my theory  is that the frequent sublingual dosages provides NMN directly to the bloodstream, independent of Liver NAD+. Bypassing the liver NAD+ pathway and providing NMN directly to the bloodstream may be the mechanism for achieving more and faster muscle growth.  NAD+ levels in the liver may be limited, but that doesn’t limit the amount of NMN that can reach other tissues throughout the body.

Of course that is just MY THEORY. I don’t know HOW it is possible that taking NMN could actually increase vascularity and muscle mass so much – I just know that it does work, for me.

A few pictures don’t prove anything

I watched my dad slowly waste away, getting weaker day by day, wishing I could do more to help.

My goal is to let everyone know about these amazing results and what it can mean for older individuals to stave off the sarcopenia that slowly robs them of their quality of life.  I don’t want to wait years for researchers to prove it.

I KNOW this works for restoring muscle in older individuals. But I also know almost no-one is going to believe how well it works, except family and friends who have seen the results. I want to speed up the discovery process.

We need real, verifiable proof.

We believe Sublingual NMN is the MOST IMPORTANT HEALTH DISCOVERY in decades.

But we don’t want to wait for 5-10 years for researchers to prove it. We want to elicit some proof of results from our customers to help show the world how effective it is.

We now have 3 programs ongoing:


We provide our NMN powder and sublingual tablets to 40 people, with cash prizes up to $2,000 each for those that demonstrate the most dramatic, proven results from using our product.

Our ideal is triathletes, runners, or weight-lifters who have a long history of competition that can be verified.

We are confident that taking frequent doses of NMN can help such older athletes make dramatic improvement in their performance and serve as a strong testimonial for the power of sublingual NMN.

Read more here


We hear from customers that have experienced a wide range of benefits. Some that are very common, such as improvement in skin, hair and nails. Some that are more dramatic or surprising, such as:

  • Cognitive Improvement in Dementia patients
  • Relief from Prostate Inflammation
  • Reversal of recent Menopause
  • Relief from debilitating Migraine headaches
  • Improved focus in high level gran prix driver

Of course these are all anecdotes and don’t provide as strong of proof as a verifiable record of improvement in sports, but they are interesting and may be useful for others to read about.

If you have a NMN Success story, send it in to, and use the subject line “Success Stories”.

If we use your success story, we will send you a 3 month supply of NMN as thanks for helping to get the word out.


We feel this will provide the strongest “proof” of efficacy, outside of clinical trials.

Competitive athletes are seeing great improvements in performance with NMN. Now we are looking for older athletes who are at the very top of their age groups.

If you or someone you know is an elite athlete and would like to make some money off your skills, let us know!

For more info about any of these programs, contact, or at (925) 421-1860

8 thoughts on “Bryan Nettles, 58 – Faster, stronger, healthier

  1. adultfrinendfinder.c om says:

    Admiring the dedication you put into your website and detailed information you offer.
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  2. George says:

    I had hoped someone could tell me if age-reversal (skeletal muscular level) could be expected for a pet, like a Dog (best friend) similar to the results the mice received?

  3. Allan Silliphant says:

    I have re-entered the workforce after 18 years of disability. Working as a uniformed
    security officer with a California State license. I can easily do 1000 reps with a 10 lb.arm weight. My Watch Commander calls me, his “main man” I’ll be 90 in 12.5 years. NMN, taken under the tongue, along with several other things that work well, that way, has really transformed me. I’m making far more than ever than possible on on SSA income alone. Women 30 years younger than me, usually smile in doorways. I’m serving as a security officer, in biotech labs in California. I’ve had my eyes tuned up surgically, both sides of my formerly occluded carotid arteries cleared to improve blood flow to my brain. My aunt was a head nurse in a California hospital until 95, died at 101, my uncle an airman in the Royal Canadian Flying Corp in WW1, lived to almost 98. I take lots of liquid Qunol coQ10, & do curls, as well. My neck skin has smoothed out, by about 90% by doing jaw work-out with MNM under my tongue. I’m over 6’1” at 180 lbs.I could be a senior model for police uniforms, now. This new lifestyle is a hoot, & I never get tired while on duty overnight. This stuff works…indeed!

  4. nebilbehar says:

    Thank you Bryan, we are a group of physicians in London over 40 who came across nmn last year and have been taking at very modest doses 100-250 mg daily in tablet form. We all felt the benefit but the older among us felt it more even at these doses. My mother was able to dance after being effectively bed bound for several years!
    We want to give it to our older patients recovering from major surgery who suffer with sarcopenia but a trial is virtually impossible with all the red tape. Ordering from US is really impractical… we need it in pharmacies in UK to direct patients and relatives.
    I completely agree sublingual and frequent doses are the way forward for now at least until slow release subcutaneous depot injections are invented or the epigenetic manipulation that allows us to produce it ourselves.
    Is there any barrier to you bringing this product to UK shelves?

    Many thanks
    Nebil Behar
    Consultant Laparoscopic and Emergency Surgeon Chelsea and Westminster hospital London UK

  5. kumbarillatree says:

    I like doing one armed push ups and my performance has improved on the regular NMN capsules. The most I ever did was 37 on each arm but that was back when I first started doing them at age 35. I’m now 47 and after a couple of months taking NMN recently reached 35 on each arm and still feel like I’m getting stronger. 27 was the most I could do before and only on a good day. I have a few bottles of the new sublingual pills on order which will arrive in the next few days. Thanks for the testimonial Bryan. I too have noticed more energy and strength. Certainly more muscle mass even though I was only taking 5-6 of the regular NMN Pure capsules a day. I figured 5-6 was the human equivalent dosage from the mouse trials after reading a lot of articles. I’ve followed the research since a bunch of studies came out in 2014 about something in blood being suspected of rejuvenating mice. So happy to be at the forefront of this revolutionary vitamin supplement research. I’ve always hated running but now do it every day. I can touch my toes immediately even if I haven’t tried in days. Usually takes me a minute or two. Can sit down for long periods without feeling stiff and sore after getting up. I’ve just about forgotten all my aches and pains and where they were. Only my dodgy knee remains and I hardly ever even notice that any longer. I used to box as a teenager and worked in security for 10 years but although I used to exercise maniacally in my twenties I certainly wasn’t a professional athlete so I won’t be submitting myself for the testimonial program but thanks for providing your heartening story Bryan.

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