NAD+ Forums

Twice daily 500 mg resveratrol for 60 days significantly decreased fasting blood sugar, hemoglobin A1c (HbA1c), and a marker for oxidative stress, malondialdehyde, in patients with type 1 diabetes. Resveratrol has been reported to be beneficial against diabetes complications. The objective of this s...

Here is a research published yesterday about rising the cellular NAD+ level by transforming lactate into pyruvate in the bloodstream. An elevated intracellular NADH:NAD+ ratio, or ‘reductive stress’, has been associated with multiple diseases, including disorders of the mitochondrial electron transp...

This new study shows that 10 day NR treatment is sufficient to prevent hearing loss in mouse models of progeria. Age-related hearing loss (ARHL) is one of the most common disorders affecting elderly individuals. There is an urgent need for effective preventive measures for ARHL because none are cur...

This new study shows that 10 day NR treatment is sufficient to prevent hearing loss in mouse models of progeria. Age-related hearing loss (ARHL) is one of the most common disorders affecting elderly individuals. There is an urgent need for effective preventive measures for ARHL because none are curr...

And the methylation clock starts ticking when we were embryos

An increase in the probability of death has been a defining feature of aging, yet human perinatal mortality starts high and decreases with age. Previous evolutionary models suggested that organismal aging begins after the onset of reproduction. However, we find that mortality and incidence of disea...

1. TAME trial: metformin will not be the best anti-aging drug but will pave the regulatory way for future anti-aging trials with "real" anti-aging endpoints 2. Dog Aging Project: this clinical trial will demonstrate significant effects of rapamycin on lifespan and the onset of age-related diseases i...

Thank you, Jocko. A few weeks ago, Dr. Kirkland (leader of senolytics study in Mayo) had a talk in my school about the translation of senolytic drugs. So excited to see the result of the clinical trials!

There are evidences show that NMN can ameliorate imflamation and depression. Some people also claim that NMN can improve sleep quality. So, good news is you are at right place.

According to Professor David Sinclair, you should consider take 1 gram of NMN daliy.

Thank you AlbertY! Great paper. Reading it now with a hot mug of instant espresso (yes, instant coffee contains more beneficial polyphenols than fresh coffee. Instant is more concentrated in caffeic acid and chlorogenic acid for example). The neuroscientist Mark Mattsson, Dr Satchin Panda at the Sa...