Search found 7 matches

by topdog999
Sat Sep 21, 2019 11:33 am
Forum: Nutrition
Topic: Blueberries (anthocyanins) reverse brain ageing
Replies: 11
Views: 4349

Re: Blueberries (anthocyanins) reverse brain ageing

Blueberries indeed are an incredible superfood.The amount needed in one's diet varies to get it's main ingredient-pterostilbene which is intensely studied for anti-neoplastic, anti-oxidant, anti-diabetic, cardiac function and other key metabolic cellular processes. It is chemically similar to resver...
by topdog999
Sat Sep 21, 2019 11:00 am
Forum: Nutrition
Topic: Natural mTOR-inhibitors for longevity
Replies: 9
Views: 2944

Re: Natural mTOR-inhibitors for longevity

Bioavailablity is the key to acheiving high levels in the target cells for any supplement to work. Strong clinical evidence, especially studies with large sampling sizes are important. Purity of the supplement- what agency verifies this, also important. Supplements don't require the strict scrutiny ...
by topdog999
Sat Sep 14, 2019 4:12 pm
Forum: NAD+
Topic: NAD+ IV increases NAD+ levels in blood plasma 400% in humans
Replies: 12
Views: 4858

Re: NAD+ IV increases NAD+ levels in blood plasma 400% in humans

Resvertrol vs pterostilbene ?? which is more easier for the body to absorb, Ive heard conflicting reports? Also I am taking a supplement from France called Prostaphane (sulforaphane)with nmn and nad+. Is any else heard of or taking this supplement with positive results? Sinclair has said that despi...
by topdog999
Sat Sep 14, 2019 12:19 pm
Forum: Longevity
Topic: NEW (Peter Attia) interview with Dr David Sinclair about longevity, how he takes NMN, sirtuins, metformin and resv
Replies: 17
Views: 4775

Re: NEW interview with Dr David Sinclair about longevity, how he takes NMN, sirtuins, metformin and resveratrol and more

Regarding Oral vs Sublingual use of NMN, Sinclair says there is good in both. m1:55 - No good answers on sublingual or not. Microbiome removes a lot of the nicotinomide from NMN and NR before it's taken up by the gut but it makes sense not to put it all through the gut. Some NMN does get through th...
by topdog999
Sat Sep 14, 2019 12:14 pm
Forum: Longevity
Topic: NEW (Peter Attia) interview with Dr David Sinclair about longevity, how he takes NMN, sirtuins, metformin and resv
Replies: 17
Views: 4775

Re: NEW interview with Dr David Sinclair about longevity, how he takes NMN, sirtuins, metformin and resveratrol and more

Many studies have shown increased bioavailability of pterostilbene vs resveratrol. Pterostilbene chemically has two methoxy (OCH3) groups attached to the molecules which has shown to increase oral absorption. Pterostilbene is the main antioxidant in blueberries. Some studies have also show NR taken ...
by topdog999
Mon Sep 09, 2019 7:10 am
Forum: Healthy Aging News and Research
Topic: Anyone is taking rapamycin or metformin?
Replies: 23
Views: 7029

Re: Anyone is taking rapamycin or metformin?

There are many documented studies that berberine mimics the effect of metformin. Studies have been done which include berberine's ability to stimulate AMP protein kinase (AMPK) which can affect insulin sensitivity, lowering of triglycerides, lowering of blood glucose anti-inflammatory effects, anti-...
by topdog999
Tue Aug 20, 2019 5:01 pm
Forum: NMN
Topic: What's your NAD? How do you test?
Replies: 7
Views: 2330

Re: What's your NAD? How do you test?

Yes, there does not seem to be commercially available tests in the USA currently, I asked my family M.D. same question and he was not aware of any. They are determining levels in laboratory studies, a recent article published in 7/5/19 in Scientific Reports concerneng safety of Niagen (nicotinamide ...