Search found 67 matches

by vandan
Sun Nov 17, 2019 5:56 pm
Forum: NMN
Topic: The first NMN study in humans is published
Replies: 17
Views: 5138

Re: The first NMN study in humans is published

The single oral administration of NMN capsules in the doses 100, 250 and 500 mg in 10 healthy Japanese men was shown to be safe. oh, your cut and past missed the first and important sentence.... Recent studies have revealed that decline in cellular nicotinamide adenine dinucleotide (NAD+) levels ca...
by vandan
Sun Nov 17, 2019 5:49 pm
Forum: NMN
Topic: The first NMN study in humans is published
Replies: 17
Views: 5138

Re: The first NMN study in humans is published

The single oral administration of NMN capsules in the doses 100, 250 and 500 mg in 10 healthy Japanese men was shown to be safe. "Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men" The administration of nic...
by vandan
Sun Nov 17, 2019 5:28 pm
Forum: NAD+
Topic: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
Replies: 7
Views: 3744

Re: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

Did you check out the article he posted? The link is there and it explains how NMN turns into NAD in the cell. Thanks Fred (sort of), my question is simply - what is the difference between taking NMN (and having it metabolised into NAD+) and taking it as NAD+, if any. There are no human trials of o...
by vandan
Sun Nov 17, 2019 3:01 pm
Forum: NAD+
Topic: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
Replies: 7
Views: 3744

Re: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

It is an exciting time for NAD+ especially in the field of aging. I agree that NAD+ holds some of the factors that can slow the aging process. In fact in Alzheimer’s disease it has been shown through animal models that DNA damage can be repaired, improved cognition and motor function can be achieve...
by vandan
Sat Nov 16, 2019 5:11 pm
Forum: NAD+
Topic: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
Replies: 7
Views: 3744

Re: NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

It is an exciting time for NAD+ especially in the field of aging. I agree that NAD+ holds some of the factors that can slow the aging process. In fact in Alzheimer’s disease it has been shown through animal models that DNA damage can be repaired, improved cognition and motor function can be achieve...
by vandan
Thu Nov 14, 2019 9:50 pm
Forum: NMN
Topic: The magic 500mg threshold :)
Replies: 50
Views: 22805

Re: The magic 500mg threshold :)

I agree wholeheartedly. NAD+ seems to enhance my sleep where NMN with me, has a stimulating effect. :shock: I am not following sorry. Isn't NAD+ just one step further down the metabolism pathway than NMN? FYI - my finger and toe nails didn't harden until I started taking NAD+(know I can see a disti...
by vandan
Thu Nov 14, 2019 9:47 pm
Forum: NMN
Topic: The magic 500mg threshold :)
Replies: 50
Views: 22805

Re: The magic 500mg threshold :)

This topic is most enlightening. Firstly, the brain is a powerful tool and like Newage, I just haven't seemed to age mentally since hitting 50 and my body has responded in kind. Second, as with all supplements I take, I space them throughout the day so my body can process just that dosage. With res...
by vandan
Thu Nov 14, 2019 9:43 pm
Forum: NAD+
Topic: NAD+ Nasal Spray Dosage
Replies: 28
Views: 12675

Re: NAD+ Nasal Spray Dosage

Hey guys has anyone here tried the new product Cenergy yet? I just got a bottle and been on it now for 2 days. So far so good other than alittle discomfort if you do more than 2 sprays per nostril. I will keep you posted on results noted. I have just finished my first bottle, very happy with the re...
by vandan
Wed Nov 13, 2019 8:07 pm
Forum: NMN
Topic: The NMN transporter is found: how NMN gets into cells
Replies: 6
Views: 2130

Re: The NMN transporter is found: how NMN gets into cells

I haven´t seen this posted before so adding it for those who haven´t read it. The elusive NMN transporter is found Lindsay E. Wu & David A. Sinclair Nature Metabolism volume 1, pages8–9(2019) Strategies to restore levels of the enzyme cofactor nicotinamide adenine dinclueotide (NAD) late in life to...
by vandan
Wed Nov 13, 2019 8:05 pm
Forum: NMN
Topic: Post your weight and dosage thread
Replies: 32
Views: 9487

Re: Post your weight and dosage thread

It's already been posted in the forum, but i'm referencing it here - worth a watch if you haven't already: https://www.youtube.com/watch?v=5DtWqzalEnc&feature=youtu.be& From the comments, referencing a study done "Older mice that were given NMN (300 mg/kg/day) experienced delayed aging in the liver...