Search found 5 matches

by drpatrick
Tue Dec 03, 2019 1:06 am
Forum: Healthy Aging News and Research
Topic: Is aging really a disease?
Replies: 12
Views: 6776

Re: Is aging really a disease?

a particular quality, habit, or disposition regarded as adversely affecting a person or group of people. Middle English (in the sense ‘lack of ease; inconvenience’): from Old French desaise ‘lack of ease’, from des- (expressing reversal) + aise ‘ease’. We consider diabetes, cancer, dementia, heart ...
by drpatrick
Thu Nov 21, 2019 1:03 am
Forum: Healthy Aging News and Research
Topic: Can Boosting NAD+ Cause Negative Effects for Certain Gene Mutations?
Replies: 6
Views: 4138

Re: Can Boosting NAD+ Cause Negative Effects for Certain Gene Mutations?

Hi James, here are a few key sentences from the interesting article mentioned by Drdavid: Increased NAD levels enhance glycolysis and fuel cancer cells. In fact, nicotinamide phosphoribosyltransferase (Nampt), a rate-limiting enzyme for NAD synthesis in mammalian cells, is frequently amplified in se...
by drpatrick
Wed Nov 20, 2019 2:57 pm
Forum: NMN
Topic: Baseline NMN/NAD+ level?
Replies: 14
Views: 6338

Re: Baseline NMN/NAD+ level?

hsCRP is a marker of inflammation and higher levels are associated with increased risk of heart disease. hsCRP can increase in any state of inflammation, including recent illness, so could reasonably get a few levels and take the lowest one as your baseline. Telomere length is not available in Canad...
by drpatrick
Wed Nov 20, 2019 2:48 pm
Forum: Miscellaneous Topics
Topic: Timing Blood Pressure Meds for maximum benefits
Replies: 2
Views: 3468

Re: Timing Blood Pressure Meds for maximum benefits

In my work as a hospitalist, I often switch patients' anti-hypertensive medication from morning to bedtime for improved control. It doesn't always work, but often helps.
by drpatrick
Wed Nov 20, 2019 2:41 pm
Forum: NAD+ Optimizers
Topic: Acute Nerve pain
Replies: 34
Views: 31607

Re: Acute Nerve pain

I would consider using an injection of PRP, platelet rich plasma, in this situation. It is very safe as it is autologous and can help with healing and regeneration of tissue. This is also known as the O-Shot. An additional benefit is that it would likely help if there is any degree of urinary incont...