Other NAD+ BoostersMetformin and Resveratrol in the Management of Diabetes

Fred

Metformin and Resveratrol in the Management of Diabetes

Post by Fred » Sat Mar 21, 2020 6:31 am

Anything that protects against diabetes also protects against aging.

"The cumulative evidence strongly supports the comparative effects of metformin and resveratrol in ameliorating diabetes-associated complications in preclinical settings.

In particular, both compounds showed strong ameliorative effects against hyperglycemia, dyslipidemia, insulin resistance, a pro-inflammatory response, and lipid peroxidation in various experimental models of diabetes.

Enhancing intracellular antioxidant capacity in addition to activating NAD-dependent deacetylase sirtuin-1 (SIRT1) and AMP-activated protein kinase (AMPK) are the prime mechanisms involved in the therapeutic effects of these compounds.

Of interest, preclinical evidence also demonstrates that the combination treatment with these compounds may have a greater efficacy in protecting against diabetes."

"Exploring the Comparative Efficacy of Metformin and Resveratrol in the Management of Diabetes-Associated Complications: A Systematic Review of Preclinical Studies"

https://www.mdpi.com/2072-6643/12/3/739/htm


Drdavid
Posts: 701
Joined: Thu Aug 15, 2019 9:59 am

Re: Metformin and Resveratrol in the Management of Diabetes

Post by Drdavid » Thu Mar 26, 2020 7:23 am

Fred thanks for sharing this research. I had seen this and have used resveratrol with many diabetic patients. I do believe that this supplement provides many benefits for the patient
drkris69
Posts: 563
Joined: Tue Aug 20, 2019 2:41 pm

Re: Metformin and Resveratrol in the Management of Diabetes

Post by drkris69 » Fri Mar 27, 2020 7:09 pm

All the more reason to keep taking Resveratrol. Thanks.
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