NAD+New research shows that NAD+ supplementation can slow Wernersyndrome (a progeria disease) in mice

User avatar
AlbertY
Posts: 152
Joined: Mon Aug 12, 2019 4:01 pm
Location: Boston, MA

New research shows that NAD+ supplementation can slow Wernersyndrome (a progeria disease) in mice

Post by AlbertY » Sun Dec 08, 2019 1:27 pm

In a new study in the scientific journal Nature Communications, an international team of researchers from, among others, the University of Copenhagen and the National Institutes of Health in the United States, has come closer to a new way of attacking the disease. The researchers have looked at a clean-up process in the cells called mitophagy. Mitophagy breaks down defective mitochondria - the cell's energy factories - and reuses the proteins that they are made up of.

'We are showing for the first time that Werner Syndrome is due to errors in the clean-up process. When we improve the clean-up by giving supplements of the drug NAD+, we can show in animal models that it increases lifespan and delays the aging processes', says Professor Vilhelm Bohr from the Center for Healthy Aging, the University of Copenhagen, and the National Institutes of Health, who had led the study.

The researchers have looked closely at the clean-up processes in blood samples from patients with Werner Syndrome, in banana flies and in roundworms with the syndrome. In addition, they have also tested NAD+ in the animal models.

https://www.eurekalert.org/pub_releases ... 112919.php


Ph.D. student at Harvard Medical School, doing research on aging
rhett
Posts: 141
Joined: Wed Sep 18, 2019 1:39 pm

Re: New research shows that NAD+ supplementation can slow Wernersyndrome (a progeria disease) in mice

Post by rhett » Sun Dec 08, 2019 8:28 pm

So if NAD+ can slow accelerated aging, then there’s a decent chance...
Post Reply Previous topicNext topic