NMNNMN reduces metabolic impairment in male mice offspring to obese mothers

Fred

NMN reduces metabolic impairment in male mice offspring to obese mothers

Post by Fred » Sun Mar 29, 2020 11:26 pm

Maternal obesity impacts offspring metabolism. We sought to boost mitochondrial energy metabolism using the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) to treat metabolic impairment induced by maternal and long-term post weaning over-nutrition.


https://www.ncbi.nlm.nih.gov/pubmed/32218167


canadahealthy
Posts: 200
Joined: Tue Aug 20, 2019 5:31 pm

Re: NMN reduces metabolic impairment in male mice offspring to obese mothers

Post by canadahealthy » Sun Jun 07, 2020 9:07 pm

Fred wrote:
Sun Mar 29, 2020 11:26 pm
]Maternal obesity impacts offspring metabolism. We sought to boost mitochondrial energy metabolism using the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) to treat metabolic impairment induced by maternal and long-term post weaning over-nutrition.


Overall this finding suggests short term administration of NMN could be a therapeutic approach for treating metabolic disease due to maternal and post weaning over-nutrition, even in late adulthood
Well i hope what's good for mice is good for humans. Working in late adulthood suggests that NMN simply directs the metabolism to behave properly.
ChrisBON
Posts: 50
Joined: Mon Sep 16, 2019 6:09 pm

Re: NMN reduces metabolic impairment in male mice offspring to obese mothers

Post by ChrisBON » Thu Jun 25, 2020 7:45 pm

Fred wrote:
Sun Mar 29, 2020 11:26 pm
Maternal obesity impacts offspring metabolism. We sought to boost mitochondrial energy metabolism using the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) to treat metabolic impairment induced by maternal and long-term post weaning over-nutrition.


https://www.ncbi.nlm.nih.gov/pubmed/32218167
I like this study, it hints that generational problems can be addressed or perhaps even corrected with NMN. Obesity related metabolism can run rampant in families, it would be nice if this could be corrected at the cellular level.
Taking:
NMN since June, 2019 (started at 250mg, 500mg as of Oct 1st)
NAD+ nasal spray since July, 2019
Resveratrol since Sept 2019
Astaxanthin 10mg since October 20th
Blueberry concentrate 500 mg since October 20th
Berberine 250 mg since October 20th
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