NMNNMN is apparently good for the liver

PaulN
Posts: 3
Joined: Tue Aug 06, 2019 5:27 pm

NMN is apparently good for the liver

Post by PaulN » Wed Aug 07, 2019 7:28 am

NMN and another favourite ( Sildrenafil) improves fenestrations in the liver ( which decline in age and contributes to insulin resistance) https://www.ncbi.nlm.nih.gov/pubmed/30285464


riott
Posts: 1
Joined: Wed Aug 07, 2019 10:21 am

Re: NMN is apparently good for the liver

Post by riott » Wed Aug 07, 2019 10:23 am

This is the first time I've heard of Sildenafil. Can you provide info for me to learn more?
NewLifeScience
Posts: 258
Joined: Thu Aug 22, 2019 4:17 pm

Re: NMN is apparently good for the liver

Post by NewLifeScience » Sat Aug 24, 2019 8:44 am

riott wrote:
Wed Aug 07, 2019 10:23 am
This is the first time I've heard of Sildenafil. Can you provide info for me to learn more?
I think the study quoted above is noting the similar behavior of many medications and compounds, including the Viagara-type pill Sildenafil, which is a vaso-dilator, statins (like simvastatin) and even blood pressure drugs (like amlodipine) versus a supplement like NMN.

Given the choice of all these types, I'd lean toward the use of a supplement.
Taking:
Resveratrol 400mg since June 2019; 600mg since October 1; 800mg since January 2020
NMN Sublingual 250mg since june 2019 500mg since September 2019
NAD+ Nasal, appx 100mg per day since September 2019; 200mg per day beginning mid November
Youvion
Posts: 10
Joined: Fri Aug 23, 2019 3:55 am

Re: NMN is apparently good for the liver

Post by Youvion » Tue Aug 27, 2019 4:22 am

Here is some additional research on how NAD+ supplementation is good for the liver, specifically fatty liver disease.

https://www.ncbi.nlm.nih.gov/pubmed/28254760

In this paper they describe a supplementation regiment that consists of NR (before the days of NMN being readily available) to up regulate mitochondria in the liver, L-Carnitine to accelerate fat transport to the mitochondria to be burned as fuel, and Serine and NAC to combat the increase in reactive oxide species created by the high fat burning liver mitochondria.

It is sort of a one-two-three punch to reduce fat deposits in the liver. At least it works for mice!

I have been taking this regiment daily for the past couple years. No ill effects, but I haven't had my liver fat tested in a while.
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