"Meanwhile, taurine increased NAD+/NADH ratio，promoted the expression of SIRT1 and suppressed p53 acetylation."
https://pubmed.ncbi.nlm.nih.gov/3201791 ... ctivation/
NaHS is precursor to H2S which activate NAMPT. A lot of people are using Taurine as a replacement for NaHS (probably accounts for the increased NAD+/NADH ratio).
It looks like our bodies manufacture Taurine in large quantities. The Wiki says it accounts for 0.1% of our total body weight. I think this is one Senolytic you don't need to buy.