SenolyticsMayo Clinic Human Trial using Fisetin

ChrisBON
Posts: 40
Joined: Mon Sep 16, 2019 6:09 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by ChrisBON » Thu Nov 07, 2019 8:50 am

Hmm.

So they are testing this for elderly frailty?

I wonder if it would be safe for my mother (83) to take the booster that has fisetin...

may be twice per week?


Taking:
NMN since June, 2019 (started at 250mg, 500mg as of Oct 1st)
NAD+ nasal spray since July, 2019
Resveratrol since Sept 2019
Astaxanthin 10mg since October 20th
Blueberry concentrate 500 mg since October 20th
Berberine 250 mg since October 20th
rhett
Posts: 124
Joined: Wed Sep 18, 2019 1:39 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by rhett » Fri Dec 13, 2019 9:20 pm

Curious if anyone has thoughts about nmn use while doing the mayo clinic fisetin protocol. Any risk of nmn propping up the senescent cells fisetin is supposed to clear?
smokinjoe
Posts: 62
Joined: Sun Sep 01, 2019 9:24 am

Re: Mayo Clinic Human Trial using Fisetin

Post by smokinjoe » Sat Dec 14, 2019 4:37 pm

rhett wrote:
Fri Dec 13, 2019 9:20 pm
Curious if anyone has thoughts about nmn use while doing the mayo clinic fisetin protocol. Any risk of nmn propping up the senescent cells fisetin is supposed to clear?
I think Fisetin and NMN are on the same team

ABN sells a NAD+ booster with AMPK activators which includes fisetin:

https://alivebynature.com/product-categ ... optimizer/
Male, 41
no i don't smoke :)

taking:
NAD+ nasal since August 15, 2019
NMN powder, 125 mg per day; 625 per day since Oct 1, 2019
Resveratrol 600mg, since September 15, 2019
CeeJayBee
Posts: 92
Joined: Thu Aug 22, 2019 4:19 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by CeeJayBee » Fri Jan 31, 2020 3:02 pm

So... Fisetin is a powerful. Senolytic?

Let's say someone has kidney failure or liver cirrhosis
Does a Senolytic potential assist with tissue generation?
User avatar
jocko6889
Posts: 166
Joined: Tue Jul 23, 2019 11:35 pm
Location: Tulsa, OK
Contact:

Re: Mayo Clinic Human Trial using Fisetin

Post by jocko6889 » Fri Jan 31, 2020 6:06 pm

CeeJayBee wrote:
Fri Jan 31, 2020 3:02 pm
So... Fisetin is a powerful. Senolytic?

Let's say someone has kidney failure or liver cirrhosis
Does a Senolytic potential assist with tissue generation?
It could indirectly by clearing a path, so to speak. Look into apocynin as well. This is good to take after a senolytic like Fisetin to assist in generation of new stem cells, as well as NMN.
CeeJayBee
Posts: 92
Joined: Thu Aug 22, 2019 4:19 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by CeeJayBee » Fri Jan 31, 2020 7:09 pm

jocko6889 wrote:
Fri Jan 31, 2020 6:06 pm
CeeJayBee wrote:
Fri Jan 31, 2020 3:02 pm
So... Fisetin is a powerful. Senolytic?

Let's say someone has kidney failure or liver cirrhosis
Does a Senolytic potential assist with tissue generation?
It could indirectly by clearing a path, so to speak. Look into apocynin as well. This is good to take after a senolytic like Fisetin to assist in generation of new stem cells, as well as NMN.
I found a little about apocynin on Wiki, where does one acquire something like this?
User avatar
jocko6889
Posts: 166
Joined: Tue Jul 23, 2019 11:35 pm
Location: Tulsa, OK
Contact:

Re: Mayo Clinic Human Trial using Fisetin

Post by jocko6889 » Fri Jan 31, 2020 9:04 pm

I bought mine on eBay.
NewLifeScience
Posts: 213
Joined: Thu Aug 22, 2019 4:17 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by NewLifeScience » Sat Feb 01, 2020 4:09 pm

rhett wrote:
Fri Dec 13, 2019 9:20 pm
Curious if anyone has thoughts about nmn use while doing the mayo clinic fisetin protocol. Any risk of nmn propping up the senescent cells fisetin is supposed to clear?
This is good thinking and it could be why Fisetin is administered in large doses for 2 days (triggering autophagy) and quite possibly NMN and NAD+ use would be suspended.
Taking:
Resveratrol 400mg since June 2019; 600mg since October 1; 800mg since January 2020
NMN Sublingual 250mg since june 2019 500mg since September 2019
NAD+ Nasal, appx 100mg per day since September 2019; 200mg per day beginning mid November
drkris69
Posts: 462
Joined: Tue Aug 20, 2019 2:41 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by drkris69 » Sun Feb 02, 2020 5:14 pm

Im gonna order some Fisetin and do the two day protocol. Jocko during those two days do you eat normally or do you have to fast? Im really interested in doing this.
CeeJayBee
Posts: 92
Joined: Thu Aug 22, 2019 4:19 pm

Re: Mayo Clinic Human Trial using Fisetin

Post by CeeJayBee » Sun Feb 02, 2020 9:39 pm

ChrisBON wrote:
Thu Nov 07, 2019 8:50 am
Hmm.

So they are testing this for elderly frailty?

I wonder if it would be safe for my mother (83) to take the booster that has fisetin...

may be twice per week?
I think that test is going on, but i am not sure it is confirmed. I have read it has very little side effects, but the elderly are more vulnerable.
Post Reply Previous topicNext topic