NAD+NAD+ Research Archive

Drdavid
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NAD+ Research Archive

Post by Drdavid » Wed Jan 15, 2020 6:57 am

Please use this thread as a deposit site for NAD+ research. It will allow new members to access research in a convenient manner


Drdavid
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Re: NAD+ Research Archive

Post by Drdavid » Wed Jan 15, 2020 6:59 am

Braidy N, Berg J, Clement J, et al. Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. Antioxid Redox Signal. 2019;30(2):251–294. doi:10.1089/ars.2017.7269
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277084/
Drdavid
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Re: NAD+ Research Archive

Post by Drdavid » Wed Jan 15, 2020 7:01 am

Antioxid Redox Signal. 2019 Feb 20;30(6):890-905. doi: 10.1089/ars.2017.7445. Epub 2018 Feb 7.
NAD+ Deficiency Is a Common Central Pathological Factor of a Number of Diseases and Aging: Mechanisms and Therapeutic Implications.
Zhang M1,2, Ying W1,2.

https://www.ncbi.nlm.nih.gov/pubmed/29295624
Fred

Re: NAD+ Research Archive

Post by Fred » Wed Jan 15, 2020 7:50 am

Great idea David. But wouldn't a section called "NAD+ research" in the forum be even better? I don't post NAD papers under the current "NAD+" section since it is devoted to just oral and IV NAD supplementation.
Drdavid
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Re: NAD+ Research Archive

Post by Drdavid » Fri Jan 17, 2020 7:22 am

Fred wrote:
Wed Jan 15, 2020 7:50 am
Great idea David. But wouldn't a section called "NAD+ research" in the forum be even better? I don't post NAD papers under the current "NAD+" section since it is devoted to just oral and IV NAD supplementation.
Fred I think this is a great idea. Do you know can we elevate this thread or does a new one need started?
Fred

Re: NAD+ Research Archive

Post by Fred » Fri Jan 17, 2020 10:18 am

Drdavid wrote:
Fri Jan 17, 2020 7:22 am
Fred wrote:
Wed Jan 15, 2020 7:50 am
Great idea David. But wouldn't a section called "NAD+ research" in the forum be even better? I don't post NAD papers under the current "NAD+" section since it is devoted to just oral and IV NAD supplementation.
Fred I think this is a great idea. Do you know can we elevate this thread or does a new one need started?
I believe only the admins (and perhaps moderators, I don´t know) can make a new permanent section in the forum.
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jocko6889
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Re: NAD+ Research Archive

Post by jocko6889 » Fri Jan 17, 2020 11:14 am

Dr David, this was a great idea. You may have noticed we started another thread called simply "NAD+Research" in 2 parts, where we put a lot of articles Bryan had accumulated.
The idea was to merge what you're doing here with that larger body of work. Waiting for input on Bryan to see what he thinks but would appreciate any input or thoughts. Would this be useful to you?
Drdavid
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Re: NAD+ Research Archive

Post by Drdavid » Mon Jan 20, 2020 7:21 am

Yes, having a simple place to accumulate research and point people to it would be fantastic. As the research volume grows it will be a great place for people to come and see the data
drkris69
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Re: NAD+ Research Archive

Post by drkris69 » Mon Jan 20, 2020 1:38 pm

I agree and love the idea guys, great stuff!
Drdavid
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Re: NAD+ Research Archive

Post by Drdavid » Wed Jan 22, 2020 7:08 am

Albert posted this research on another thread:
The conceptual evolution of nicotinamide adenine dinucleotide (NAD+) from being seen as a simple metabolic cofactor to a pivotal cosubstrate for proteins regulating metabolism and longevity, including the sirtuin family of protein deacylases, has led to a new wave of scientific interest in NAD+. NAD+ levels decline during ageing, and alterations in NAD+ homeostasis can be found in virtually all age-related diseases, including neurodegeneration, diabetes and cancer. In preclinical settings, various strategies to increase NAD+ levels have shown beneficial effects, thus starting a competitive race to discover marketable NAD+ boosters to improve healthspan and lifespan. Here, we review the basics of NAD+ biochemistry and metabolism, and its roles in health and disease, and we discuss current challenges and the future translational potential of NAD+ research.
https://www.nature.com/articles/s42255-019-0161-5
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