NMNThe magic 500mg threshold :)

drkris69
Posts: 210
Joined: Tue Aug 20, 2019 2:41 pm

Re: The magic 500mg threshold :)

Post by drkris69 » Mon Oct 21, 2019 3:36 pm

Newlife, you should try 1g of NMN daily. I FEEL STRONG LIKE BULL...... :o


Newage
Posts: 425
Joined: Thu Aug 22, 2019 10:22 pm

Re: The magic 500mg threshold :)

Post by Newage » Mon Oct 21, 2019 7:46 pm

drkris69 wrote:
Mon Oct 21, 2019 6:21 am
Thats awesome newage! Congrats to you sir. Ive had an ultrasound done as well, checking my venous structures in both legs. Newage you are a true inspiration to all of us. :D
Thank you drkris69
NAD+ Sublingual & NAD+ Nasal Spray finally arrived in the post today.
Racing home to organise the daily dosage protocol.
Will advise forum of results as I transition over to NAD+ from old favourite NMN...
Time will tell... and I will advise accordingly. ;)
drkris69
Posts: 210
Joined: Tue Aug 20, 2019 2:41 pm

Re: The magic 500mg threshold :)

Post by drkris69 » Tue Oct 22, 2019 5:39 am

I can't wait to hear from you newage. Im predicting you will favor NMN in the end.
Newage
Posts: 425
Joined: Thu Aug 22, 2019 10:22 pm

Re: The magic 500mg threshold :)

Post by Newage » Tue Oct 22, 2019 9:53 am

drkris69 wrote:
Tue Oct 22, 2019 5:39 am
I can't wait to hear from you newage. Im predicting you will favor NMN in the end.
You may be right with that prediction drkris69.
Time will tell.
But in saying that “Nothing ventured nothing gained” :idea:
I am a relative light sleeper so looking to see if the NAD+ has a positive effect on the quality of sleep as Drdavid suggests...
drkris69
Posts: 210
Joined: Tue Aug 20, 2019 2:41 pm

Re: The magic 500mg threshold :)

Post by drkris69 » Tue Oct 22, 2019 10:55 am

Yes newage.....time will tell..
rhett
Posts: 48
Joined: Wed Sep 18, 2019 1:39 pm

Re: The magic 500mg threshold :)

Post by rhett » Sat Nov 09, 2019 12:25 am

Another interesting point in the latest Dr Sinclair interview with Rhonda Patrick, he mentioned that there may be a minimum dose needed to overcome the liver's ability to metabolize nmn as it comes in. So if the liver can only metabolize 250mg (a guess) then anything above that will get sent out into the bloodstream. This could account for the "threshold" effect that so many people have noticed. Below the threshold and your liver just eats it all up.
Newage
Posts: 425
Joined: Thu Aug 22, 2019 10:22 pm

Re: The magic 500mg threshold :)

Post by Newage » Sat Nov 09, 2019 4:47 am

drkris69 wrote:
Tue Oct 22, 2019 5:39 am
I can't wait to hear from you newage. Im predicting you will favor NMN in the end.
It’s the weekend so no supplements at all including Alive By Nature Products.
As great as I feel from Monday to Friday, funnily enough I feel even better when I have a break over the weekend.
Hmmm..You would think that this means that there is a benefit to having a one or two day break from all supplements per week.
My personal observations only..

My Daily Dosage as of next Monday is:
500 mg Sublingual NAD+ Tablets
200 mg NAD+ Nasal Spray
375 mg NMN Sublingual Tablets
Plus complimentary supplements... :idea:
Taytaytay195
Posts: 37
Joined: Mon Aug 12, 2019 5:32 pm

Re: The magic 500mg threshold :)

Post by Taytaytay195 » Sat Nov 09, 2019 8:32 am

Newage wrote:
Sat Nov 09, 2019 4:47 am
drkris69 wrote:
Tue Oct 22, 2019 5:39 am
I can't wait to hear from you newage. Im predicting you will favor NMN in the end.
It’s the weekend so no supplements at all including Alive By Nature Products.
As great as I feel from Monday to Friday, funnily enough I feel even better when I have a break over the weekend.
Hmmm..You would think that this means that there is a benefit to having a one or two day break from all supplements per week.
My personal observations only..

My Daily Dosage as of next Monday is:
500 mg Sublingual NAD+ Tablets
200 mg NAD+ Nasal Spray
375 mg NMN Sublingual Tablets
Plus complimentary supplements... :idea:
I agree. I use 375 Mg sublingual every other day with exercise, metformin every off day from that, and Sundays nothing but exercise. This is a recent change and i feel great.
drkris69
Posts: 210
Joined: Tue Aug 20, 2019 2:41 pm

Re: The magic 500mg threshold :)

Post by drkris69 » Sat Nov 09, 2019 9:55 am

I agree with the 2-day break from all supplements. I believe that the body in sense resets itself in those two days.
Drdavid
Posts: 300
Joined: Thu Aug 15, 2019 9:59 am

Re: The magic 500mg threshold :)

Post by Drdavid » Sun Nov 10, 2019 11:03 am

I havent decided if I buy into the whole take two days off regimen. We have been playing with this for about 30 days now on several people and have not shown any significant changes. I will continue to let you know as we produce data from this experiment.
The threshold appears to be real and does not seem to change much for each person. As more studies are complete I think we will understand this mechanism more. However, I do hear many of you talking about either or scenarios. I think the current research shows that we should probably be taking both NAD and a precursor in order to get superior results. They each work on different chemical cascades and can influence physiology in different ways. Please keep this in the back of your mind as you develop your regimen.
A final thought for anyone new to NMN is that do not take this product before sleep. It will alter your sleep cycle and keep you awake. I have found that I have about a 4 hours window between last dose and the ability to fall asleep.
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